Improved variational Bayes inference for transcript expression estimation
نویسندگان
چکیده
منابع مشابه
Improved variational Bayes inference for transcript expression estimation.
RNA-seq studies allow for the quantification of transcript expression by aligning millions of short reads to a reference genome. However, transcripts share much of their sequence, so that many reads map to more than one place and their origin remains uncertain. This problem can be dealt using mixtures of distributions and transcript expression reduces to estimating the weights of the mixture. I...
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ژورنال
عنوان ژورنال: Statistical Applications in Genetics and Molecular Biology
سال: 2014
ISSN: 1544-6115,2194-6302
DOI: 10.1515/sagmb-2013-0054